enlighten和acquaint的区别主要在于含义及用法上。enlighten作为及物动词，含义为“启发”、“开导”、“阐明”；acquaint同样作为及物动词，含义为“使熟悉”、“使了解”。
一、enlighten的含义及用法
enlighten作为及物动词，译为启发;开导;阐明。
例句：Can you enlighten her on this subject?
对这个问题你能启发启发她吗？
She didn't enlighten him about her background.
她未向他讲明自己的出身背景。
It was an elite that believed its task was to enlighten the multitude.
精英人物都会认为自己的职责就是启迪群众。
If you know what is wrong with her, please enlighten me.
如果你知道她出什么问题了，请告诉我。
The teacher's words made me at once become enlightened.
老师的一席话使我顿开茅塞。
Peter thought the world was flat until I enlightened him.
在我开导彼特以前，他认为地球是扁平的。
This spring will probably be enlightening for a lot of people.
这个春天可能会启发很多人。
二、acquaint的含义及用法
acquaint作为及物动词，译为使熟悉;使了解。
例句：You will first need to acquaint yourself with the filing system.
你首先需要熟悉文件归档方法。
The students are already acquainted with the work of Shakespeare.
这些学生已经读过莎士比亚的著作。
Employees should be fully acquainted with emergency procedures.
雇员应当十分熟悉应急措施。
The meetings were a way to get acquainted with each other.
这些会议是一种相互结交的途径。
I want to acquaint myself with your strengths and weaknesses.
我想知道你有哪些长处以及不足。
She has to acquaint her new boss with recent happenings in the company.
她得告诉新老板公司近来的动态。
She wants to acquaint herself with your strengths and weaknesses.
她想知道你有哪些长处以及不足。
